• John O Mason, Peter L Goodwin, Richard M Feist, and Rachel S Vail.
• Department of Ophthalmology, University of Alabama at Birmingham School of Medicine, Callahan Eye Foundation Hospital, USA.
• Ophthal Surg Las Im. 2007 May 1;38(3):203-8.

Background And ObjectivesTo determine whether irrigation of the sub-Tenon's space with anesthetic agents during pars plana vitrectomy (PPV) involving general anesthesia decreases postoperative pain, analgesic use, or nausea.Patients And MethodsA prospective, controlled trial of 46 consecutive patients requesting general anesthesia for PPV who were randomized to receive or not receive a sub-Tenon's space injection prior to surgery. A mixture of 3 mL of 2% lidocaine with hyaluronidase and 3 mL of 0.5% bupivacaine was used to induce local blockade. Pain, postoperative nausea, and analgesia use were evaluated.ResultsLocal blockade did not significantly alter the proportion of reported pain at 30 minutes and 2, 4, and 24 hours after the operation. The local blockade had no effect on reducing postoperative nausea or the number of patients requiring pain medication.ConclusionsLocal blockade prior to surgery in patients undergoing PPV under general anesthesia does not significantly decrease postoperative pain, analgesic use, or nausea.

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