• Scott W Sharkey, Denise C Windenburg, John R Lesser, Martin S Maron, Robert G Hauser, Jennifer N Lesser, Tammy S Haas, James S Hodges, and Barry J Maron.
• Hypertrophic Cardiomyopathy Center and Cardiovascular Research Division, Minneapolis Heart Institute Foundation, Minneapolis, Minnesota 55407, USA.
• J. Am. Coll. Cardiol. 2010 Jan 26;55(4):333-41.

ObjectivesThis study was designed to define more completely the clinical spectrum and consequences of stress cardiomyopathy (SC) beyond the acute event.BackgroundStress cardiomyopathy is a recently recognized condition characterized by transient cardiac dysfunction with ventricular ballooning.MethodsClinical profile and outcome were prospectively assessed in 136 consecutive SC patients.ResultsPatients were predominantly women (n = 130; 96%), but 6 were men (4%). Ages were 32 to 94 years (mean age 68 +/- 13 years); 13 (10%) were 2 months in 5%. Right and/or left ventricular thrombi were identified in 5 patients (predominantly by CMR imaging), including 2 with embolic events. Three patients (2%) died in-hospital and 116 (85%) have survived, including 5% with nonfatal recurrent SC events. All-cause mortality during follow-up exceeded a matched general population (p = 0.016) with most deaths occurring in the first year.ConclusionsIn this large SC cohort, the clinical spectrum was heterogeneous with about one-third either male, Copyright (c) 2010 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

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