• Acta Anaesthesiol Scand · Jan 1978

    Comparative Study

    EEG-changes during general anaesthesia with enflurane (Efrane) in comparison with ether.

    • A Persson, E Peterson, and A Wåhlin.
    • Acta Anaesthesiol Scand. 1978 Jan 1;22(4):339-48.

    AbstractThe effects of enflurane (efrane) and ether on the cerebral functions were studied by EEG on two similar groups of adult patients. For basic comparison a depth of anaesthesia was chosen which permitted abdominal surgery without the need to administer muscular relaxants. At this level of anaesthesia the typical EEG-changes of paroxysmal type which have been described with enflurane were seen only occasionally. If, however, the depth of anaesthesia was further increased, such EEG-changes indicating increased cerebral excitability were seen more often under enflurane and also appeared under ether anaesthesia. No seizure activity was recorded.

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