• Lynda Facchiano and Charlene Hoffman Snyder.
• Mayo Clinic Arizona, Scottsdale, Arizona 85259, USA. facchiano.lynda@mayo.edu
• J Am Assoc Nurse Pract. 2013 Jan 1;25(1):24-31.

PurposeUnderstanding the critical appraisal process allows nurse practitioners (NPs) to determine a study's reliability, validity, and applicability to their client(s)/families, and to their clinical practice setting. The purpose of this final part of this four-part evidence-based practice (EBP) series is designed to utilize a clinical scenario that will walk the NP through EBP steps 1 through 3 while providing an example of how to critically appraise a randomized control trial.Data SourcesScientific literature review, gray literature, PubMed and other online literature databases and resources, and online EBP websites.ConclusionsAs healthcare providers, our role is to provide the best possible care we can to our client(s) and their families. One way to do this is through the utilization of the EBP process. When EBP processes are integrated into our clinical practice settings it augments the existing provider-client relationship and shared decision-making process.Implications For PracticeIt is hoped that this four-part series enhanced NPs' understanding of the EBP processes of developing a clinical inquiry, searching for the best evidence, critically appraising the evidence, and integrating EBP into clinical practice.©2012 The Author(s) Journal compilation ©2012 American Association of Nurse Practitioners.

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