• Mt. Sinai J. Med. · Dec 2006

    Case Reports

    Intracranial hemorrhage associated with methanol intoxication.

    • Ahmet Sebe, Salim Satar, Belkan Uzun, Metin Topal, Hasan Yesilagac, and Andakkan Avci.
    • Cukurova University, School of Medicine, Department of Emergency Medicine, 01330 Balcali/Adana, Turkey.
    • Mt. Sinai J. Med. 2006 Dec 1;73(8):1120-2.

    AbstractMethanol is a common component of gasoline, antifreeze, washer fluid, perfume, household cleaners and various other industrial products. Acute methanol poisoning produces severe metabolic acidosis, serious neurologic sequelae and rarely imaging findings. In this paper, we describe a 35-year-old man with methanol intoxication who was in a comatose stage. Computed tomography (CT) showed widespread brain edema and hemorrhages localized in the supratentorial region of the temporal lobe, nearly 3 x 1 cm in a crescent shape, in the white matter surrounding the capsula externa and extending to the periventricular white matter and occipital lobes. Temporal lobe hemorrhage in our patient might also have been due to the effect of heparinization during hemodialysis, metabolic and lactic acidosis, or formate.

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