• Acta Anaesthesiol Scand · Aug 1988

    Randomized Controlled Trial Clinical Trial

    The reduction of pain on injection of propofol: the effect of addition of lignocaine.

    • S Helbo-Hansen, V Westergaard, B L Krogh, and H P Svendsen.
    • Odense University Hospital, Department of Anaesthesiology, Denmark.
    • Acta Anaesthesiol Scand. 1988 Aug 1;32(6):502-4.

    AbstractThe effects of addition of 1 ml of lignocaine (10 mg) or isotonic saline to 19 ml of the emulsified preparation of propofol (Diprivan) were studied in a randomised, double-blind trial in 80 patients. The incidence and severity of pain on injection of propofol were significantly reduced by the addition of lignocaine (P less than 0.01).

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