• West Afr J Med · Jul 2002

    Comparative Study

    A comparison of the efficacy of alfentanil and remifentanil analgesic infusions for spinal surgery.

    • A F Faponle and J W H Watt.
    • Department of Anaesthesia, Obafemi Awolowo University, Ile-Ife, Nigeria.
    • West Afr J Med. 2002 Jul 1;21(3):180-2.

    AbstractThe use of alfentanil infusion was compared with that of remifentanil infusion for spinal cord surgery in a retrospective review. The aim was to compare the outcome when methohexitone was used as the only hypnotic agent in the two groups. Over a 3-year period, 5 patients (group 1) had Alfentanil infusion and 11 patients (group 2) had remifentanil infusion for analgesia during spinal cord surgery. Results showed that remifentanil lead to a faster onset of recorvery than alfentanil. It also provided better haemodynamic stability than alfentanil without excesive hypotension (p > 0.05). Our experience here indicated that remifentanil provided better flexibility of use with less tachycardia and respiratory depression than alfentanil for spinal surgery.

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