• Scand J Plast Recons · Mar 1994

    Randomized Controlled Trial Comparative Study Clinical Trial

    Alkalisation of lignocaine-adrenaline reduces the amount of pain during subcutaneous injection of local anaesthetic.

    • F Samdal, K Arctander, K C Skolleborg, and P F Amland.
    • Department of Plastic Surgery, Norwegian National Hospital, Oslo.
    • Scand J Plast Recons. 1994 Mar 1;28(1):33-7.

    AbstractA double blind, randomised controlled trial was performed to compare the amount of pain experienced after subcutaneous infiltration of lignocaine with adrenaline, and the same anaesthetic buffered to pH 7.1-7.3, in patients undergoing liposuction (n = 8), blepharoplasty (n = 7), mammaplasty (n = 6), and in volunteers (n = 10). A linear analogue pain scale was used to access pain. In all four groups the buffered solution caused significantly less pain (p < 0.001 except for mammaplasty--p = 0.02).

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