• Br J Anaesth · Dec 1984

    Case Reports

    Occurrence of malignant hyperpyrexia in a patient with osteogenesis imperfecta.

    • A J Rampton, D A Kelly, E C Shanahan, and G S Ingram.
    • Br J Anaesth. 1984 Dec 1;56(12):1443-6.

    AbstractProbable malignant hyperpyrexia (MH) developed and was successfully treated in a 20-yr-old man during anaesthesia for reduction of a fractured mandible. The sister of this patient had died after an anaesthetic at the age of 14 yr, but malignant hyperpyrexia was not suspected. Subsequent enquiries revealed that the patient and his sister both had osteogenesis imperfecta. This case illustrates the infrequently reported association of malignant hyperpyrexia with osteogenesis imperfecta, and the difficulties in obtaining an adequate personal and family history of previous anaesthetics.

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