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Case Reports
Pulmonary Necrobiotic Nodules in Crohn's Disease: A Rare Extra-intestinal Manifestation.
- Karim El-Kersh, Mostafa Fraig, Rodrigo Cavallazzi, Mohamed Saad, and Rafael L Perez.
- Department of Pulmonary, Critical Care, and Sleep Disorders Medicine kaelke01@louisville.edu.
- Respir Care. 2014 Dec 1;59(12):e190-2.
AbstractPulmonary necrobiotic nodules represent a rare extra-intestinal manifestation of Crohn's disease. Histologically, they are composed of sterile aggregates of inflammatory cells with necrosis. The differential diagnosis is broad, and exclusion of infectious etiologies is mandatory before starting immunosuppressive therapy. Here, we present the fifth reported case of pulmonary necrobiotic nodules in Crohn's disease. Our patient had new-onset Crohn's disease associated with both cavitating and non-cavitating lung nodules that were confirmed to be necrobiotic nodules by biopsy. The patient was started on mesalamine and prednisone, with subsequent improvement of his gastrointestinal symptoms and regression of the necrobiotic nodules.Copyright © 2014 by Daedalus Enterprises.
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