• M Y Obraztsov, V V Kuzkov, P I Lenkin, A A Klyagin, O Yu Ivashchenko, M M Sokolova, N Ya Shemyakina, A R Grushitsyn, V M Gorenkov, and M Yu Kirov.
• Anesteziol Reanimatol. 2015 May 1;60(3):43-8.

UnlabelledBACKGROUND AND OBJECTVE: Carotid endarterectomy (CEE) is an effective surgical technique to prevent cerebral ischemia and stroke, but can be associated with intervention-related complications. The surgical shunting of the intervention area may reduce the risk of the intraoperative ipsilateral cerebral ischemia following the carotid artery clamping but is controversial. The goal of this study was to compare the cerebral tissue oxygen saturation (SctO2) and early changes of cognitive functions in CEE in the settings of transient vascular bypass and without this method.Methods45 adult patients were randomized to either the bypass group (the Bypass group, n = 24) or the Controls / No Bypass (the Control group, n = 21). All patients were monitored for invasive arterial pressure, SpO, EtCO,, and cerebral oxygenation (SctO2, Fore-Sight, CASMED, USA) over the contra- and ipsilateral frontal head areas. The cognitive functions were assessed using series of Montreal Cognitive Assessment score (MoCA) before the intervention, and on 6 and 36 hrs after the CEE.ResultsWe did not find intergroup differences in the surgery duration, degree of stenosis and baseline cognitive function. The values of SctO2 reduced significantly only above contralateral side; these changes were attenuated in the shunt group. There were no intergroup differences in postoperative cognitive function.ConclusionEmpiric transient vascular bypass during carotid endarterectomy did not result in significant changes of the ipsilateral cerebral oxygenation, hyperperfusion and cognitive function, but attenuated the decrease of SctO2 over the contralateral hemisphere.

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