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J. Invest. Dermatol. · Dec 2010
CommentLucky number seven: RNase 7 can prevent Staphylococcus aureus skin colonization.
- John S Cho, Caiyun Xuan, and Lloyd S Miller.
- Division of Dermatology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
- J. Invest. Dermatol. 2010 Dec 1;130(12):2703-6.
AbstractStaphylococcus aureus colonization is a major risk factor for infection. In this issue, Simanski et al. demonstrate that the antimicrobial peptide RNase 7 is essential for preventing S. aureus colonization in human skin. These findings suggest that therapeutic interventions aimed at targeting RNase 7 production in the skin may be a novel strategy to protect against S. aureus infections.
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