• J P Pell, J M Sirel, A K Marsden, I Ford, and S M Cobbe.
• Department of Medical Cardiology, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER.
• BMJ. 2001 Jun 9;322(7299):1385-8.

ObjectivesTo determine the association between ambulance response time and survival from out of hospital cardiopulmonary arrest and to estimate the effect of reducing response times.DesignCohort study.SettingScottish Ambulance Service.SubjectsAll out of hospital cardiopulmonary arrests due to cardiac disease attended by the Scottish Ambulance Service during May 1991 to March 1998.Main Outcome MeasuresSurvival rate to hospital discharge and potential improvement from reducing response times.ResultsOf 13 822 arrests not witnessed by ambulance crews but attended by them within 15 minutes, complete data were available for 10 554 (76%). Of these patients, 653 (6%) survived to hospital discharge. After other significant covariates were adjusted for, shorter response time was significantly associated with increased probability of receiving defibrillation and survival to discharge among those defibrillated. Reducing the 90th centile for response time to 8 minutes increased the predicted survival to 8%, and reducing it to 5 minutes increased survival to 10-11% (depending on the model used).ConclusionsReducing ambulance response times to 5 minutes could almost double the survival rate for cardiac arrests not witnessed by ambulance crews.

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