• Clin. Chim. Acta · Oct 2013

    Review

    Salivary mental stress proteins.

    • Konen Obayashi.
    • Diagnostic Unit for Amyloidosis, Department of Laboratory Medicine, Kumamoto University Hospital, 1-1-1 Honjo, Kumamoto 860-8556, Japan. Electronic address: konen@fc.kuh.kumamoto-u.ac.jp.
    • Clin. Chim. Acta. 2013 Oct 21;425:196-201.

    AbstractOf the major diagnostic specimen types, saliva is one of the most easily collected. Many studies have focused on the evaluation of salivary proteins secreted by healthy people and patients with various diseases during responses to acute mental stress. In particular, such studies have focused on cortisol, α-amylase, chromogranin A (CgA), and immunoglobulin A (IgA) as salivary stress markers. Each of these salivary stress markers has its own strengths and weaknesses as well as data gaps related to many factors including collection technique. In this review, we summarize the critical knowledge of the positive and negative attributes and data gaps pertaining to each salivary stress marker.© 2013.

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