• Resuscitation · May 2006

    Transoesophageal cardiac pacing is effective for cardiopulmonary resuscitation in a rat of asphyxial model.

    • Feng-Qing Song, Lu Xie, and Meng-Hua Chen.
    • Institute of Cardiovascular Diseases, The First Affiliated Hospital of Guangxi Medical University, Nanning 530021, PR China.
    • Resuscitation. 2006 May 1;69(2):263-8.

    ObjectiveTo investigate effectiveness of transoesophageal cardiac pacing in a rat model of asphyxial cardiac arrest.MethodsTen minutes after the tracheal tube had been clamped, cardiac arrest (CA) occurred in 20 Sprague-Dawley rats, and the rats were assigned randomly to receive cardiopulmonary resuscitation (CPR) in a control group or CPR combined with transoesophageal cardiac pacing in a pacing group. Restoration of spontaneous circulation (ROSC) was defined as an unassisted pulse with a mean arterial pressure (MAP) of >or=20 mmHg for >or=1 min.ResultsROSC was significantly more frequent in the pacing group compared with the control group (7/10 versus 1/10, P<0.05). Faster ROSC and longer survival trend in the pacing group were seen compared with the control group.ConclusionTransoesophageal cardiac pacing is effective for CPR in a rat of asphyxial model. However, the precise mechanism is not clear and further experiments will be necessary.

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