• Minerva anestesiologica · Nov 2015

    Review

    Complications of immunosuppressive agents therapy in transplant patients.

    • A Reske and M Metze.
    • Fachkrankenhaus Coswig GmbH, Division of Anesthesiology and Intensive Care Medicine, Coswig, Germany - michael.metze@web.de.
    • Minerva Anestesiol. 2015 Nov 1; 81 (11): 1244-61.

    AbstractSolid organ transplantation remains the gold standard for the treatment of end-stage organ dysfunction and saves thousands of lives. Besides the progress of surgery, advances in understanding transplant physiology, immunology and the development of immunosuppressive drugs lead to improved short- and long-term survival. Transplantation is offered to an increasing number of patients with higher age and comorbidities. Approximately one third of organ recipients require hospital readmission after transplantation because of a multitude of clinical problems related to immunosuppressive therapy. We review the current knowledge on typical complications associated with immunosuppressants with emphasis on the intensivist's perspective.

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