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Rev Esp Anestesiol Reanim · Feb 2013
Multicenter Study[Blood transfusion during heart surgery. A retrospective nested case-control study].
- J R Pérez-Valdivieso, P Monedero, N García-Fernández, M Vives, F J Lavilla, M Bes-Rastrollo, and Grupo Español de Disfunción Renal en Cirugía Cardiaca (GEDRCC).
- Departamento de Anestesia y Reanimación, Clínica Universidad de Navarra, Universidad de Navarra, Pamplona, España. jrpvaldi@unav.es
- Rev Esp Anestesiol Reanim. 2013 Feb 1;60(2):79-86.
ObjectiveTo assess the correlation between intraoperative packed red blood cells transfusion and adverse outcome in a Spanish cohort of cardiac surgery patients.MethodsRetrospective observational multicentre study. An analysis was performed on the data from 927 cardiac surgery patients treated in 24 Spanish hospitals in 2007. Patients who received intraoperative transfusions were compared with non-transfused patients. Multivariate analyses were performed (including, among others, several items from the Euroscore, surgery type, basal renal status and haemoglobin levels, and Thakar score).ResultsEvery transfusion of packed red cells was associated with increased postoperative risk of acute kidney damage at 72 hours after surgery, prolonged mechanical ventilation, and need for haemodynamic support. Moreover, transfused patients showed an increased in-hospital mortality rates (Adjusted OR: 1.30; 95% CI: 1.19-1.42), as well as longer hospital stays (almost 4 days).ConclusionsIn this cohort of patients, intraoperative transfusion might independently predict higher risk of early acute kidney damage, prolonged postoperative mechanical ventilation, and a need for haemodynamic support, and reduced short term survival (adjusted OR for mortality: 1.30; 95% CI: 1.19-1.42), and longer hospital stays (4 days longer).Copyright © 2012 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Published by Elsevier España, S.L. All rights reserved.
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