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- Anil A Thomas, Sevag Demirjian, Brian R Lane, Matthew N Simmons, David A Goldfarb, Vairavan S Subramanian, and Steven C Campbell.
- Glickman Urological and Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
- Urology. 2011 Jan 1;77(1):5-11.
AbstractUrologists are integrally involved in the management of acute kidney injury (AKI), which is common after renal surgery or secondary to postrenal (obstructive) etiologies. The measurement of serum creatinine is a suboptimal indicator of AKI because it lags behind acute changes in renal function. Recent advances indicate that serum/urine biomarkers will prove useful for early detection of AKI, analogous to the use of cardiac enzymes for acute myocardial infarction. These serum/urine markers may guide future therapy, facilitate research efforts to reduce the severity of AKI, such as after partial nephrectomy, and allow for more accurate prognostication for patients with AKI.Copyright © 2011 Elsevier Inc. All rights reserved.
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