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- Matthew A Koenig.
- The Queen's Medical Center, Neuroscience Institute, 1301 Punchbowl Street, QET5, Honolulu, HI 96813, USA. Electronic address: mkoenig@queens.org.
- Crit Care Clin. 2014 Oct 1;30(4):765-83.
AbstractBrain injury represents the major cause of long-term disability and mortality among patients resuscitated from cardiac arrest. Brain-directed therapies include maintenance of normal oxygenation, hemodynamic support to optimize cerebral perfusion, glycemic control, and targeted temperature management. Pertinent guidelines and recommendations are reviewed for brain-directed treatment. The latest clinical trial data regarding targeted temperature management are also reviewed. Contemporary prognostication among initially comatose cardiac arrest survivors uses a combination of clinical and electrophysiologic tests. The most recent guidelines for prognostication after cardiac arrest are reviewed. Ongoing research regarding the effects of induced hypothermia on prognostic algorithms is also reviewed.Copyright © 2014 Elsevier Inc. All rights reserved.
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