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Intensive care medicine · Jul 1996
Case ReportsInorganic fluoride concentration after long-term sedation with isoflurane.
- M A Osborne, J M Eddleston, and W McNicoll.
- Intensive Care Unit, Withington Hospital, Manchester, UK.
- Intensive Care Med. 1996 Jul 1;22(7):677-82.
AbstractWe report on five patients in whom long-term sedation with isoflurane for up to 7 days was used successfully. Serum inorganic fluoride concentrations were measured daily. The concentrations ranged from 12 mmol l-1 to 29 mmol l-1. These were well below the described renal toxic level of 50 mmol l-1. There was no deterioration in renal function attributable to the use of isoflurane.
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