• J Consult Clin Psychol · Aug 2000

    Randomized Controlled Trial Multicenter Study Clinical Trial

    Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy.

    • J D Teasdale, Z V Segal, J M Williams, V A Ridgeway, J M Soulsby, and M A Lau.
    • Medical Research Council Cognition and Brain Sciences Unit, Cambridge, United Kingdom. john.teasdale@mrc-cbu.cam.ac.uk
    • J Consult Clin Psychol. 2000 Aug 1;68(4):615-23.

    AbstractThis study evaluated mindfulness-based cognitive therapy (MBCT), a group intervention designed to train recovered recurrently depressed patients to disengage from dysphoria-activated depressogenic thinking that may mediate relapse/recurrence. Recovered recurrently depressed patients (n = 145) were randomized to continue with treatment as usual or, in addition, to receive MBCT. Relapse/recurrence to major depression was assessed over a 60-week study period. For patients with 3 or more previous episodes of depression (77% of the sample), MBCT significantly reduced risk of relapse/recurrence. For patients with only 2 previous episodes, MBCT did not reduce relapse/recurrence. MBCT offers a promising cost-efficient psychological approach to preventing relapse/recurrence in recovered recurrently depressed patients.

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