• Emilios Andrikos, Paraskevi Tseke, Olga Balafa, Dinna N Cruz, Afrodite Tsinta, Marianthi Androulaki, Michael Pappas, and Claudio Ronco.
• Department of Nephrology, Hatzikosta Hospital, Ioannina, Greece.
• Blood Purif. 2009 Jan 1;28(3):239-44.

Background And AimAcute kidney injury (AKI) is a common complication in intensive care units (ICUs). However, its incidence and outcome vary in several studies depending on definitions used or even the geographic origin of the study. We aimed to evaluate the epidemiology of AKI in ICUs in Greece.MethodProspective multicenter study of ICU patients presented with AKI during a 3-month period.ResultsOne-hundred and seventy patients presented with AKI (16% of total admissions in 23 ICUs). The most common contributing factor to AKI was sepsis (45%). Half of the patients required renal replacement therapy, which was mainly managed by ICU clinicians. Nearly 65% of the AKI patients died, whereas 15% were discharged with renal impairment. Age (RR 1.01, p = 0.046), sepsis (RR 1.62, p = 0.015) and urine output (RR 0.99, p = 0.009) were independently associated with outcome.ConclusionAKI involves a large number of patients in Greek ICUs and is associated with adverse outcomes.Copyright 2009 S. Karger AG, Basel.

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