• Gastrointest. Endosc. · Jul 2013

    Comparative Study

    Delay in performing ERCP and adverse events increase the 30-day readmission risk in patients with acute cholangitis.

    • Udayakumar Navaneethan, Norma G Gutierrez, Ramprasad Jegadeesan, Preethi G K Venkatesh, Mujtaba Butt, Madhusudhan R Sanaka, John J Vargo, and Mansour A Parsi.
    • Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
    • Gastrointest. Endosc. 2013 Jul 1;78(1):81-90.

    BackgroundReadmission to the hospital within 30 days of discharge (30-day readmission rate) is used as a quality measure.ObjectiveTo investigate the incidence and factors that contribute to readmissions in patients with acute cholangitis.DesignRetrospective cohort study.SettingTertiary-care referral center.PatientsRetrospective analysis of consecutive patients admitted to our center for acute cholangitis and ERCP.Intervention Ercp Main Outcome MeasurementsIncidence and variables associated with 30-day readmission and 1-year mortality.ResultsERCP was successful in 98.8% of patients during the index admission. The 30-day readmission rate was 22.0%. Recurrence of cholangitis was the most common etiology for readmissions (37.8%). Readmission within 30 days was independently associated with failed ERCP or ERCP delayed for >48 hours (odds ratio [OR] 2.47; 95% confidence interval [CI], 1.01-6.07), development of any after-ERCP adverse event (OR 11.0; 95% CI, 3.06-39.30), and the etiology of cholangitis (etiologies not related to stones) (OR 3.3; 95% CI, 1.17-9.18). Every 1-point increase in the Charlson Comorbidity Index score (OR, 1.33; 95% CI, 1.05-1.69) was associated significantly with 1-year mortality. In unadjusted analysis, 30-day readmission after ERCP was associated significantly with 1-year mortality (OR, 2.86; 95% CI, 1.16-7.07). This association, however, was not present after adjustment for other covariates.LimitationsRetrospective study.ConclusionDelays in performing ERCP during the index admission, development of after-ERCP adverse events, and etiology of cholangitis not related to stones increased the risk of 30-day readmissions.Copyright © 2013 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.

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