• Am J Hosp Palliat Care · May 2018

    Treatment of Postherpetic Pain With Scrambler Therapy, a Patient-Specific Neurocutaneous Electrical Stimulation Device.

    • Thomas J Smith and Giuseppe Marineo.
    • 1 Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD, USA.
    • Am J Hosp Palliat Care. 2018 May 1; 35 (5): 812-813.

    ObjectivesPostherpetic neuropathy (PHN) is common, severe, and often refractory to treatment. We treated 10 patients with refractory PHN using Scrambler therapy, a neurocutaneous stimulation device that delivers "nonpain" information with surface electrodes.MethodsScrambler therapy was given as 30-minute sessions daily for 10 days. Pain was recorded before and after treatment. Two centers.ResultThe average pain score rapidly diminished from 7.64 ± 1.46 at baseline to 0.42 ± 0.89 at 1 month, a 95% reduction, with continued relief at 2 and 3 months. Patients achieved maximum pain relief with less than 5 treatments.DiscussionScrambler therapy appears to have a promising effect on PHN, with prompt and continued relief and no side effects. Further research is warranted.

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