• Anaesthesia · May 1996

    Randomized Controlled Trial Comparative Study Clinical Trial

    Topical ibuprofen for skin analgesia prior to venepuncture.

    • A J Smith, K A Eggers, and M R Stacey.
    • Department of Anaesthesia, University Hospital of Wales, Cardiff.
    • Anaesthesia. 1996 May 1;51(5):495-7.

    AbstractThe analgesic effect of topical ibuprofen was investigated in ten volunteers. There were no significant differences in visual analogue scale pain scores for pinprick after 15 and 60 min of application of ibuprofen, placebo and EMLA cream. Comparison of visual analogue scale scores for venous cannulation after similar durations of ibuprofen and EMLA creams found significantly (p < 0.014) lower scores for EMLA at 60 min. We do not consider ibuprofen cream to be clinically useful for venous cannulation.

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