• Wenhua He, Yin Zhu, Pi Liu, Liang Xia, Yong Zhu, Hao Zeng, and Nonghua Lyu.
• Department of Gastroenterology, the First Affiliated Hospital of Nanchang University, Nanchang 330006, China.
• Zhonghua Nei Ke Za Zhi. 2016 Jan 1; 55 (1): 21-4.

ObjectiveTo compare the discrepancy between the new(2012) and the old (1992) Atlanta classification criteria for defining severity, organ failure and local complications in patients with acute pancreatitis (AP).MethodsDemographic, clinical and laboratory data of 2,305 consecutive AP patients with onset less than 3 days, were collected between January 2005 to December 2013 in the First Affiliated Hospital of Nanchang University. Severity, organ failure and pancreatic local complications were respectively classified by the old Atlanta classification and the new revised Atlanta classification. Multi-factor scoring system and single serum marker were recorded and calculated using the acute pancreatitis database.ResultsIn 2,305 patients with AP, there were 301 cases (13.1%) diagnosed with acute respiratory failure, 136 cases (5.9%) with shock, 105 cases (4.6%) with acute renal failure, 296 cases (12.8%) with gastrointestinal bleeding, based on the old Atlanta classification criteria. According to the severity, 900 cases (39.0%) were classified as mild acute pancreatitis (MAP), 1,405 cases (61.0%) as severe acute pancreatitis (SAP). However, based on the new Atlanta classification criteria, there were 686 cases (29.8%) with acute respiratory failure, 129 cases (5.6%) with acute renal failure, 107 cases (4.6%) with circulatory failure. Consequently, 998 cases (43.3%) were classified as MAP, 937 cases (40.7%) as moderately severe acute pancreatitis (MSAP), 370 cases (16.1%) as SAP. The incidence of respiratory failure was lower than that of the old standard. In SAP patients by new criteria, the discharge rate in critical condition and mortality were not only higher than those in MSAP patients (17.0% vs 4.1%, 4.1% vs 1.5%, respectively, all P < 0.001), but also higher than those in SAP patients by the old classification (17.0% vs 7.2%, 4.1% vs 2.1%, all P < 0.001).ConclusionsThe diagnostic criteria of organ failure are different between the new and old Atlanta classification. The SAP patients classified by the new standard have worse outcome than those by the old standard. More attention needs to be paid to critical patients stratified by the new standard.

25 keywords...

hide…