• Chad B Gunnlaugsson, Mark D Iannettoni, Bo Yu, Douglas B Chepeha, and Theodoros N Teknos.
• Department of Otolaryngology, University of Michigan, Ann Arbor, MI 48109-0312, USA.
• ORL J. Otorhinolaryngol. Relat. Spec. 2004 Jan 1;66(3):148-54.

ObjectivesTo document the treatment of refractory chyle leaks using thoracoscopic thoracic duct ligation and provide systematic guidelines to manage chyle leaks.MethodsThe medical records of 2 patients with chyle leaks are reviewed, followed by a review of the literature on chyle leaks and their thoracoscopic management.ConclusionsInitial treatment of chyle fistula is aimed at conservative medical management. Persistent high-output fistulas (>500 cm(3)) should be considered for neck reexploration as conservative management is likely to fail. Thoracoscopic thoracic duct ligation provides a safe and efficient means of treating chyle leaks refractory to repeated surgical and medical intervention. It should also be considered as a primary surgical intervention for patients with: (1) chyle output exceeding 500 cm(3)/day where prior intraoperative attempts at ligation have failed, (2) severe metabolic and nutritional complications, (3) coexisting chylothorax with respiratory compromise, and (4) low-output fistulas (<500 cm(3)/day) of long duration (>14 days).Copyright 2004 S. Karger AG, Basel

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