• Br J Anaesth · Nov 1991

    Randomized Controlled Trial Comparative Study Clinical Trial

    Ketamine for caudal analgesia in children: comparison with caudal bupivacaine.

    • M Naguib, A M Sharif, M Seraj, M el Gammal, and A A Dawlatly.
    • Department of Critical Care Medicine, Faculty of Medicine and Health Sciences, United Arab Emirates University, Al Ain.
    • Br J Anaesth. 1991 Nov 1;67(5):559-64.

    AbstractFifty children undergoing inguinal herniotomy were allocated randomly to three groups to receive a caudal injection of either 0.25% bupivacaine 1 ml kg-1 with or without ketamine 0.5 mg kg-1 or ketamine 0.5 mg kg-1 with normal saline 1 ml kg-1. There was no significant difference in quality of pain relief, postoperative behaviour or analgesic requirements between the ketamine group and the two other groups. The bupivacaine-ketamine mixture provided better analgesia than the bupivacaine solution alone. Side effects such as motor weakness or urinary retention were not observed in the ketamine group.

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