• Ivo W Soliman, Dylan W de Lange, Linda M Peelen, Olaf L Cremer, Arjen J C Slooter, Wietze Pasma, Jozef Kesecioglu, and Diederik van Dijk.
• Department of Intensive Care Medicine, University Medical Centre Utrecht, Utrecht, the Netherlands. Electronic address: I.W.Soliman@umcutrecht.nl.
• J Crit Care. 2015 Feb 1;30(1):181-6.

PurposeThe goal of this study was to describe long-term survival and health-related quality of life (HRQoL), measured by EQ-6D, in a general intensive care unit (ICU) population.Materials And MethodsWe included 5934 consecutive adult patients admitted to a mixed-population ICU. There were no exclusion criteria. One-year survival status was determined using the Dutch municipal population register. Subsequently, all survivors received the EuroQoL EQ-6D-3L questionnaire. The primary outcome was overall HRQoL and survival of the ICU survivors, compared to overall QoL of an age- and sex-matched reference population.ResultsA total of 5138 patients (86.6%) survived until hospital discharge, with 4647 (78.3%) patients surviving the 1-year of follow-up. The EuroQoL questionnaire was sent to 4465 survivors and returned by 3034 (68.0%) of 4465. The median HRQoL in surviving patients was 0.83 (interquartile range [IQR], 0.64-1.00) vs 0.86 (IQR, 0.85-0.86) in the reference population (P < .001). There was marked variation across admission diagnosis groups: cardiac surgery patients had an HRQoL of 0.94 (IQR, 0.74-1.00), whereas patients admitted with chronic renal failure had an HRQoL of 0.65 (IQR, 0.47-0.83).ConclusionsOne year after ICU admission, HRQoL was significantly lower than in the reference population. Notably, marked variations were found across subgroups.Copyright © 2014 Elsevier Inc. All rights reserved.

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