• Intensive care medicine · Dec 2014

    Comparative Study

    Outcome measures report different aspects of patient function three months following critical care.

    • Linda Denehy, Amy Nordon-Craft, Lara Edbrooke, Daniel Malone, Sue Berney, Margaret Schenkman, and Marc Moss.
    • Department of Physiotherapy, The University of Melbourne, Melbourne, Australia, l.denehy@unimelb.edu.au.
    • Intensive Care Med. 2014 Dec 1; 40 (12): 1862-9.

    BackgroundPrevious investigation of the relationship between physical performance and patient self-report physical function (PF) measures in intensive care unit (ICU) survivors have not been performed.ObjectivesTo (1) analyze the extent to which other activity-based measures of physical performance may serve as proxies for the 6-min walk test (6 MWT); (2) determine the extent to which the Short Form (SF) 36 domain of PF and physical component summary (PCS) score, reflect components of physical performance and (3) examine the relationship between demographic and ICU variables and the 6 MWT.DesignCross-sectional data from two clinical trials.SettingTwo acute care hospitals (Melbourne, Australia and Denver, USA).PatientsA total of 177 survivors of ICU.MeasurementsWere evaluated at 3 months. Performance-based measures were: 6 MWT, timed up and go test (TUG), the five times sit to stand test (5 × STS), the Berg balance scale (BBS) and two self-report measures: the SF-36 PF domain and the PCS score.Main Results6 MWT showed excellent correlation with the TUG (rho = -0.79) and BBS (rho = 0.80); and good correlation with 5 × STS (rho = -0.69) and SF-36 PF scores (rho = 0.69). 6 MWT explained 54 and 33% of variance in SF-36 PF and PCS scores respectively. No variables were clinically important in predicting 6 MWT.ConclusionsThe 6 MWT and TUG may both be acceptable measures of PF performance 3 months after ICU. Performance-based tests measure different constructs than self-report measures and choice of outcome variables should be aligned with study aims to ensure the most appropriate measure is used.

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