• Pierre-Antoine Gourraud, Roland G Henry, Bruce A C Cree, Jason C Crane, Antoine Lizee, Marram P Olson, Adam V Santaniello, Esha Datta, Alyssa H Zhu, Carolyn J Bevan, Jeffrey M Gelfand, Jennifer S Graves, Douglas S Goodin, Ari J Green, H-Christian von Büdingen, Emmanuelle Waubant, Scott S Zamvil, Elizabeth Crabtree-Hartman, Sarah Nelson, Sergio E Baranzini, and Stephen L Hauser.
• Department of Neurology, School of Medicine, University of California, San Francisco, San Francisco, CA.
• Ann. Neurol. 2014 Nov 1;76(5):633-42.

AbstractWe present a precision medicine application developed for multiple sclerosis (MS): the MS BioScreen. This new tool addresses the challenges of dynamic management of a complex chronic disease; the interaction of clinicians and patients with such a tool illustrates the extent to which translational digital medicine-that is, the application of information technology to medicine-has the potential to radically transform medical practice. We introduce 3 key evolutionary phases in displaying data to health care providers, patients, and researchers: visualization (accessing data), contextualization (understanding the data), and actionable interpretation (real-time use of the data to assist decision making). Together, these form the stepping stones that are expected to accelerate standardization of data across platforms, promote evidence-based medicine, support shared decision making, and ultimately lead to improved outcomes.© 2014 American Neurological Association.

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