• Infect Control Hosp Epidemiol · Dec 2013

    Observational Study

    Carbapenem de-escalation therapy in a resource-limited setting.

    • Anucha Apisarnthanarak, Nuntanij Bhooanusas, Apiwat Yaprasert, and Linda M Mundy.
    • Division of Infectious Diseases, Thammasat University Hospital, Pratumthani, Thailand.
    • Infect Control Hosp Epidemiol. 2013 Dec 1;34(12):1310-3.

    AbstractPulmonary infection (P=.01) and an infectious diseases consultation (P=.04) were associated with carbapenem de-escalation; pulmonary infection and septic shock were associated with unsuccessful de-escalation. Successful de-escalation was associated with lower mortality (0% vs 23%; P<.001) and shorter duration of carbapenem use (4 vs 10 days; P ≤ .001).

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