• J Stroke Cerebrovasc Dis · Jul 1997

    Changes in cerebral oxygen saturation with change in posture: a preliminary report.

    • M Misra, M Dujovny, M S Alp, K V Slavin, J I Ausman, and R A Widman.
    • Department of Neurosurgery, University of Illinois, Chicago, IL, USA.
    • J Stroke Cerebrovasc Dis. 1997 Jul 1;6(5):337-40.

    BackgroundDisease of the major vessels in the neck can disrupt autoregulation and lead to changes in the cerebral blood flow and cerebral autoregulation. These changes can be reflected by means of cerebral oxygen saturation.MethodsWe measured cerebral oxygen saturation in 20 patients with atherosclerotic disease of the carotid and vertebral arteries and compared results with 10 normal subjects. Saturation was measured using a noninvasive near-infrared device, the transcranial cerebral oximeter.ResultsThere were marked decreases in cerebral oxygen saturation in patients with carotid-vertebral artery disease when the position of the patient was changed, from supine to erect.ConclusionChanges in regional cerebral oxygen saturation inpatients with carotid-vertebral artery disease may reflect disruption of cerebral autoregulation.

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