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- Bronisław Czech, Ewa Kucewicz, and Marek Frank.
- Kliniki Kardiochirurgii i Transplantologii Slaskiego Centrum Chorób Serca w Zabrzu.
- Wiad. Lek. 2003 Jan 1;56(11-12):556-9.
Abstract2-3% of patients after cardiac procedures with the use of cardiopulmonary by-pass develop neurological complications with focal symptoms. Also to there may be mental, emotional and intellectual disturbances. This kind of complications occurs in 33-83% of patients. The post-cardiopulmonary by-pass delirium is a syndrome with diverse symptoms. Confusion, hallucinations, paranoid illusions, psycho-motoric excitation, fear may also occur. A high level of serotonin and overstimulation of 5-HT2 receptors in the central nervous system are the reason of delirium. The relief of symptoms may be achieved by intravenous administration of Ondansetron, an antagonist of 5-HT2 receptors.
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