• Fertility and sterility · May 2011

    Randomized Controlled Trial Comparative Study

    Fertility after colorectal resection for endometriosis: results of a prospective study comparing laparoscopy with open surgery.

    • Emile Daraï, Benedicte Lesieur, Gil Dubernard, Roman Rouzier, Marc Bazot, and Marcos Ballester.
    • Service de Gynécologie-Obstétrique, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, CancerEst, Université Pierre et Marie Curie, Paris, France. emile.darai@tnn.aphp.fr
    • Fertil. Steril. 2011 May 1;95(6):1903-8.

    ObjectiveTo determine whether the surgical route of colorectal resection for endometriosis is a determinant factor for fertility.DesignProspective study.SettingTertiary-care university hospital.Patient(S)Fifty-two patients with endometriosis were randomly assigned to laparoscopic or open surgery.Intervention(S)Laparoscopically assisted vs. open colorectal resection.Main Outcome Measure(S)Evaluation of fertility outcomes spontaneously and after assisted reproductive therapy.Result(S)The mean follow-up was 29 months. Among the 28 patients wishing to conceive, 11 (39.3%) became pregnant. Overall cumulative pregnancy rate at 52 months for these patients was 45.1%. For patients with or without infertility, the cumulative pregnancy rate was 37.6% and 55.6%, respectively, and the cumulative spontaneous pregnancy rate 13.3% and 36.5%, respectively. All the spontaneous pregnancies were observed in the laparoscopy group.Conclusion(S)This study demonstrates that spontaneous pregnancy is more frequent after laparoscopy compared with open surgery for colorectal endometriosis.Copyright © 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

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