• Paediatric anaesthesia · Feb 2007

    Case Reports

    Minor increase of endtidal CO2 during sevoflurane-induced malignant hyperthermia.

    • Monalisa Bonciu, Arnaud de la Chapelle, Henry Delpech, Thiery Depret, Reneé Krivosic-Horber, and Marc Raucoules Aimé.
    • Département d'Anesthésie-Réanimation Ouest, CHU Nice, Nice, France. monabonciu@yahoo.com
    • Paediatr Anaesth. 2007 Feb 1;17(2):180-2.

    AbstractMalignant hyperthermia (MH) in a pediatric patient during sevoflurane anesthesia with only a minor rise of endtidal CO(2) is described. MH was considered because of increased rectal temperature. The outcome was favorable after the initiation of a few simple measures (increased minute ventilation, cessation of sevoflurane). As recommended by the regional MH Reference Center, dantrolene was not used. In vitro contracture tests were performed on muscle biopsies from both parents. A strong contracture in response to halothane confirmed the father's MH susceptibility, thereby according a high probability of an MH episode in his son.

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