• Obstetrics and gynecology · Jun 1981

    The effect of maternal administration of ephedrine on fetal heart rate and variability.

    • R G Wright, S M Shnider, G Levinson, S H Rolbin, and J T Parer.
    • Obstet Gynecol. 1981 Jun 1;57(6):734-8.

    AbstractEphedrine is the most popular vasopressor used in obstetrics to prevent or treat spinal or epidural hypotension. Fetal heart rate (FHR) changes during epidural anesthesia were studied in 71 patients; it was found that ephedrine administration (57 patients) was associated with significant increases in FHR and beat-to-beat variability. These changes were dose related and were not associated with fetal asphyxia as judged by measurement of fetal scalp blood pH or Apgar scores.

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