• Bulletin du cancer · Jan 1988

    [The reproduction in France of Rosen's protocol for osteosarcomas].

    • M Brunat-Mentigny, M C Demaille, E Quitana, D Olive, C Bachelot, A Boitetot, J C Gentet, P Noir, H Roche, and J P Thyss.
    • Centre Léon-Bérard, Lyon, France.
    • Bull Cancer. 1988 Jan 1;75(2):201-6.

    AbstractThe authors treated 188 patients with osteosarcoma by chemotherapy followed by surgery and additional chemotherapy (Rosen's T regimen). In 14% of cases, infectious, neurologic or cardiac complications were observed, which resulted in death in 2% of the patients. Forty-six per cent responded well to the primary chemotherapy, 76% of which are alive and disease-free, as opposed to merely 42% of the bad responders.

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