• David B MacDonald and Michael Janusz.
• Section of Clinical Neurophysiology, Department of Neurosciences, King Faisal Specialist Hospital & Research Center, MBC 76, PO Box 3354, 11211 Riyadh, Saudi Arabia.
• J Clin Neurophysiol. 2002 Jan 1;19(1):43-54.

AbstractThoracoabdominal aneurysm surgery carries an approximate 10% risk of intraoperative paraplegia. Abrupt cord ischemia and the confounding effects of systemic alterations and limb or cerebral ischemia challenges neurophysiologic spinal cord monitoring. This investigation sought a rapid differential monitoring approach to predict or help prevent paraplegia. Thirty-one patients were monitored with motor evoked potentials (MEPs) and median and tibial somatosensory evoked potentials (SSEPs). MEPs involved single-pulse transcranial electrical stimulation with D wave recording (n = 16), arm and leg muscle MEPs following multiple-pulse transcranial electrical stimulation (n = 12), or both (n = 3). D wave recordings required averaging, invasive epidural electrode insertion, and produced both false positives and false negatives. Muscle MEPs were instantaneous and reliably sensitive and specific for cord ischemia. Cortical and peripheral nerve SSEPs provided rapid detection of systemic alterations and cerebral or limb ischemia. Cord and subcortical SSEPs required excessive averaging time. In conclusion, bilateral arm and leg muscle MEPs with median and tibial peripheral nerve and cortical SSEPs provide sufficiently rapid detection and differentiation of cord ischemia from confounding factors. There were two predicted intraoperative spinal cord infarctions (6.5%) and nine circumstantial examples of possible contributions to deficit prevention.

41 keywords...

hide…