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- Gilbert Lagrue, Solange Cormier, Catherine Mautrait, and Catherine Diviné.
- Hôpital Albert Chenevier, Créteil. gilbert.lagrue@ach.ap-hop-paris.fr
- Presse Med. 2006 Feb 1;35(2 Pt 1):246-8.
IntroductionAmong the symptoms that may occur with smoking withdrawal, constipation is relatively frequent, but little studied.CaseThree women reported that constipation developed when they stopped smoking and improved during transient relapses.DiscussionThis constipation sometimes produces serious functional disorders and can induce relapse. It occurs especially among women and those predisposed to it. Nicotine, by acting on the parasympathomimetic system, increases intestinal peristalsis, and a cigarette can appear to be effective self-medication. Magnesium salts are the first-line treatment for this problem. If they fail, neostigmine, an anticholinesterase with parasympathomimetic activity, appears remarkably effective in correcting this disorder.
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