-
Randomized Controlled Trial Clinical Trial
Efficacy of a small single dose of oral dexamethasone for outpatient croup: a double blind placebo controlled clinical trial.
- G C Geelhoed, J Turner, and W B Macdonald.
- Emergency Department, Princess Margaret Hospital for Children, Perth, Australia.
- BMJ. 1996 Jul 20;313(7050):140-2.
ObjectiveTo assess the efficacy of a single dose of oral dexamethasone 0.15 mg/kg in children with mild croup not admitted to hospital.DesignDouble blind, randomised, placebo controlled clinical trial.SettingThe emergency department of a tertiary paediatric hospital.Subjects100 children aged 4-122 months presenting with mild croup.InterventionA single oral dose of dexamethasone 0.15 mg/kg or placebo.Main Outcome MeasureReturn to medical care with ongoing croup.ResultsBaseline characteristics of the two treatment groups were similar. Eight children (all from the placebo group) returned to medical care with ongoing croup, one being admitted. There was no reported difference in duration of croup symptoms, duration of viral symptoms, or rate of return to medical care for other reasons.ConclusionOral dexamethasone in a dose of 0.15 mg/kg is effective in reducing return to medical care with ongoing croup in children with mild croup.
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