• Terapevt Arkh · Jan 1998

    Comparative Study Clinical Trial

    [Neuralgia and zovirax treatment of patients with herpes zoster].

    • E P Dekonenko, A S Shishov, L V Kupriianova, Iu P Rudometov, and F I Bagrov.
    • Terapevt Arkh. 1998 Jan 1;70(12):63-5.

    AimTo estimate the occurrence of postherpetic neuralgia (PHN) arising after acute period of herpes zoster (HZ) and determination of zovirax efficiency in PHN prevention.Materials And MethodsOf a total of 102 patients with HZ aged 17-89 years, 20 patients aged 26-83 years were given zovirax.ResultsAcute pain syndrome in PHN was observed in more that one-third of HZ patients. Patients over 60 years of age were more predisposed to PHN. Zovirax reduced the duration of acute rash and its healing, decreased the number of patients with zoster-associated pain and PHN patients.ConclusionZovirax is effective and safe in preventing PHN in HZ patients.

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