-
Randomized Controlled Trial Comparative Study Clinical Trial
The effects of propofol on laryngeal reactivity and the haemodynamic response to laryngeal mask insertion.
- I Acalovschi, A Miclescu, and L Bugov.
- University Department of Anaesthesia and Intensive Therapy, Spitalul Clinic, Cluj-Napoca, Romania.
- Eur J Anaesthesiol. 1995 Jul 1;12(4):351-6.
AbstractThe ease of the insertion of laryngeal mask and the haemodynamic response were assessed 2 min after induction of anaesthesia with either propofol 2.5 mg kg-1 or thiopentone 4.0 mg kg-1 in 38 ASA I premedicated patients. The inserting conditions scored as excellent, good, poor and unable to insert were significantly better with propofol than with thiopentone (P < 0.001). Insertion of the laryngeal mask was followed by a transient but significant increase in both systolic (P < 0.05) and diastolic (P < 0.01) arterial pressure in the thiopentone group; there was no comparable response in the propofol group. The heart rate varied little from baseline in both groups.
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