• Anaesth Intensive Care · Apr 1998

    Case Reports

    Central nervous system toxicity attributable to epidural ropivacaine hydrochloride.

    • A N Plowman, S Bolsin, and L E Mather.
    • Department of Anaesthesia, Geelong Hospital, Geelong.
    • Anaesth Intensive Care. 1998 Apr 1;26(2):204-6.

    AbstractRopivacaine, a new local anaesthetic agent, has been demonstrated to have less potential than bupivacaine for central nervous system toxicity on the basis of human and animal studies. We report a case of a convulsion secondary to presumed inadvertent intravascular injection of 20 mg of ropivacaine in a 44 kg patient during an epidural for chronic pain. There were minimal signs of cardiovascular toxicity.

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