• Can Fam Physician · Feb 1994

    Review

    Pharmacologic management of herpes zoster and postherpetic neuralgia.

    • F S Mamdani.
    • Department of Pharmacy, Vancouver General Hospital.
    • Can Fam Physician. 1994 Feb 1;40:321-6, 329-32.

    AbstractHerpes zoster is an infection caused by reactivation of dormant varicella-zoster virus. The acute course of herpes zoster is generally benign; however, some patients will experience postherpetic neuralgia characterized by severe, relentless, and at times disabling pain that is often refractory to treatment. While herpes zoster responds to acyclovir, cost-benefit considerations limit the drug's usefulness to only a select group. Postherpetic neuralgia requires a holistic approach, including pharmacologic therapy using several different classes of drugs.

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