[Does an injection filter modify the cranial spread of a sensory

Der Anaesthesist · Apr 1992

Randomized Controlled Trial Comparative Study Clinical Trial

[Does an injection filter modify the cranial spread of a sensory blockade in epidural anesthesia?].

In a prospective study we compared the spread of sensory blockade in epidural anaesthesia with and without Micropore filter. ⋯ A total of 32 patients undergoing varicose vein stripping under epidural anaesthesia were randomly assigned to two groups of 16 each. Bupivacaine 0.75% and POR 8 (0.1 IU/ml) were administered by means of a constant-velocity perfusor. In group A a Micropore filter was inserted between the perfusor syringe and the epidural catheter. In group B the epidural catheter was connected to the syringe without the filter. The puncture was performed at the L3-4 interspace with the patient in a sitting position. An epidural catheter was advanced 3 cm cephalad. Using the pin-prick method, the sensory level of the blockade was tested 5, 7, 10, 15, 20 and 30 min after injection of the local anesthetic solution. Statistical evaluation was performed with the t-test for unpaired samples. RESULTS. After 10 min the spread of analgesia was 5.75 +/- 1.26 segments in group A and 8 +/- 1.89 segments in group B; after 15 min it was 7.06 +/- 1.62 segments and 9.56 +/- 1.54 segments; after 20 min, 7.87 +/- 1.62 segments and 10.62 +/- 1.45 segments; and after 30 min 8.12 +/- 1.66 segments and 11.12 +/- 1.45 segments in group A and B, respectively. At any time sensory blockade was higher in group B (without Micropore filters) than in group A. The mean difference between the two groups amounted to 2-3 segments. The differences were significant at any time (P less than 0.001). These results show that the use of a Micropore filter in epidural anaesthesia leads to a reduced spread of sensory blockade. In our own examinations we found lowering of the pressure of the local anaesthetic solution that passes through the Micropore filter compared with the pressure of the solution injected without the filter. This seems to be the reason for the reduced spread of sensory blockade. Using these filters the onset of analgesia is delayed, and a given spread of analgesia needs a larger dose of local anaesthetic and is thus accompanied by a higher toxicity.

expand abstract… or not…
- U Schulte, H Nolte, and G Prippenow.
- Institut für Anästhesiologie des Klinikum Minden, Westfalen.
- Anaesthesist. 1992 Apr 1;41(4):228-30.
UnlabelledIn a prospective study we compared the spread of sensory blockade in epidural anaesthesia with and without Micropore filter.Materials And MethodsA total of 32 patients undergoing varicose vein stripping under epidural anaesthesia were randomly assigned to two groups of 16 each. Bupivacaine 0.75% and POR 8 (0.1 IU/ml) were administered by means of a constant-velocity perfusor. In group A a Micropore filter was inserted between the perfusor syringe and the epidural catheter. In group B the epidural catheter was connected to the syringe without the filter. The puncture was performed at the L3-4 interspace with the patient in a sitting position. An epidural catheter was advanced 3 cm cephalad. Using the pin-prick method, the sensory level of the blockade was tested 5, 7, 10, 15, 20 and 30 min after injection of the local anesthetic solution. Statistical evaluation was performed with the t-test for unpaired samples. RESULTS. After 10 min the spread of analgesia was 5.75 +/- 1.26 segments in group A and 8 +/- 1.89 segments in group B; after 15 min it was 7.06 +/- 1.62 segments and 9.56 +/- 1.54 segments; after 20 min, 7.87 +/- 1.62 segments and 10.62 +/- 1.45 segments; and after 30 min 8.12 +/- 1.66 segments and 11.12 +/- 1.45 segments in group A and B, respectively. At any time sensory blockade was higher in group B (without Micropore filters) than in group A. The mean difference between the two groups amounted to 2-3 segments. The differences were significant at any time (P less than 0.001). These results show that the use of a Micropore filter in epidural anaesthesia leads to a reduced spread of sensory blockade. In our own examinations we found lowering of the pressure of the local anaesthetic solution that passes through the Micropore filter compared with the pressure of the solution injected without the filter. This seems to be the reason for the reduced spread of sensory blockade. Using these filters the onset of analgesia is delayed, and a given spread of analgesia needs a larger dose of local anaesthetic and is thus accompanied by a higher toxicity.

Pubmed Copy Citation Plaintext

Add institutional full text...
Notes
Knowledge, pearl, summary or comment to share?

300 characters remaining

help

You can also include formatting, links, images and footnotes in your notes

Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.

Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.

Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.

Links can be included with: [my link to pubmed](http://pubmed.com)

Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")

For footnotes use [^1](This is a footnote.) inline.

Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..
hide…

[Does an injection filter modify the cranial spread of a sensory blockade in epidural anesthesia?].

Notes

300 characters remaining

help

You can also include formatting, links, images and footnotes in your notes

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.