• Intensive care medicine · Sep 2002

    Pulse oximeter-enhanced accuracy of capnometry in children with cyanotic heart disease.

    • Jaap W De Vries, Frans B Plötz, and A Johannes Van Vught.
    • Department of Anesthesia, Intensive Care and Pain, Mesos Medical Center, PO box 8605, 3503 RP Utrecht, The Netherlands. jwdvries@mesos.nl
    • Intensive Care Med. 2002 Sep 1; 28 (9): 1336-9.

    ObjectivesTo evaluate the relationship between the arterial end-tidal partial pressure of carbon dioxide (PCO2) difference (deltapCO2) and the degree of desaturation in children with cyanotic heart disease (CHD) and to come to a more reliable estimation of the arterial carbon dioxide partial pressure (PaCO2) from the end-tidal carbon dioxide partial pressure (PET-CO2).Design And SettingIn part retrospective, in part prospective observational study at a university children's hospital.Subjects And InterventionsWe retrospectively assessed the relationship between the arterial oxygen saturation as measured by means of pulse oximetry (SpO2) and the arterial to end-tidal PCO2 differences (deltaPCO2) from the records of medical or surgical interventions in 43 patients with CHD. We derived a PaCO2-PET-CO2 correction formula that was prospectively validated in 34 patients with CHD.Measurements And ResultsIn the retrospective part we found a significant correlation between SpO2 and deltaPCO2 ( r (2)=0.84, p<0.001). The regression equation (corrected PET-CO2=raw PET-CO2-0.36xSpO2+39) was used in the prospective part to calculate the corrected PET-CO2. The r (2)s for the correlations between PaCO(2) and uncorrected and corrected PET-CO2 were 0.17 ( p<0.05) and 0.94 ( p<0.001), respectively. The uncorrected PET-CO2 bias was 13.0 mmHg, the bias +/- 2SDs was -0.1 and 26.2 mmHg. The corrected PET-CO2 bias was -0.6 mmHg, the bias +/- 2SD's was -4.0 and 2.9 mmHg.ConclusionsCorrecting the PET-CO2 for the degree of hypoxia using the SpO2 in artificially ventilated infants and children with CHD results in a clinically applicable estimation of the PaCO2. As both SpO2 and PET-CO2 can be monitored continuously and non-invasively, this could facilitate artificial ventilation management in children with CHD.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…