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Ann Med Interne (Paris) · Oct 2002
Case Reports[Acetaminophen-induced hypothermia, an AIDS related side-effect? About 4 cases].
- Eric Denes, Monique Amaniou, Jean-Philippe Rogez, Pierre Weinbreck, and Louis Merle.
- Service de Maladies Infectieuses et Tropicales, CHU Dupuytren, 87042 Limoges, France. eric.denes@unilim.fr
- Ann Med Interne (Paris). 2002 Oct 1; 153 (6): 411-3.
AbstractHypothermia is an uncommon side effect of acetaminophen. We report 4 cases of HIV-infected patients who developed hypothermia after intravenous injection of propacetamol (the parenteral formulation of acetaminophen). The mechanism of this hypothermia is unknown. AIDS-induced changes in the metabolism of acetaminophen, could be an explanation. AIDS-associated opportunistic diseases may account for part of the mechanism. These hypothermias occur within 6 hours after the injection, are well tolerated and regress spontaneously.
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