• Gustavo Savino, Vittoria Perrotta, Daniela Colucci, Laura Balia, Maria Sammartino, Rossella Garra, Sergio Petroni, Alessandra Mastrocola, and Emilio Balestrazzi.
• Institute of Ophthalmology, Catholic University, Rome, Italy.
• J AAPOS. 2010 Apr 1; 14 (2): 124-6.

PurposeTo investigate the effects of sub-Tenon's capsule ropivacaine injection on pupillary diameter in strabismus surgery.MethodsA total of 16 patients were randomly assigned to 2 groups. The ropivacaine group (R) received sub-Tenon's ropivacaine 1% (2.5-3 mL) injections. In the control group (C), general anesthesia was induced and a saline solution (2.5-3 mL) was injected in the sub-Tenon's capsule. Pupillary diameter was measured at baseline and 2 and 5 minutes from the injections. The effects of the injections were expressed as a ratio of final (5 minutes) versus basal diameter.ResultsA significant mydriasis occurred in the ropivacaine group when compared with the control group (Group R vs Group C ratio = 2.32, p < 0.0001) or with unoperated fellow eye (R vs unoperated eye ratio = 2.29, p < 0.0001).ConclusionsRopivacaine in the sub-Tenon's capsule induces a mydriasis probably related to a pharmacological ciliary ganglion block.Copyright 2010 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.

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