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- Hua Peng, Lu Wang, Bin He, Matthew Giudice, Lin Zhang, and Zhong-Xin Zhao.
- Department of Neurology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
- Clin J Pain. 2013 Jan 1;29(1):89-91.
BackgroundHypnic headache is a rare disorder characterized by frequent nocturnal attacks of a generalized headache in the elderly.MethodThis is the first report identifying 2 Chinese hypnic headache cases according to its diagnostic criteria. Both of the patients received sodium ferulate (100 or 50 mg, 3 times/d) for 2 or 3 months.ResultsThe results of polysomnography in our cases indicated the onset of headache attacks in non-rapid eye movement sleep stage 2. Their symptoms were completely relieved for 1 year after the treatment.ConclusionOur results suggest that sodium ferulate could be a potential treatment for hypnic headache.
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